Posts Tagged ‘the best fish oil’

Osteoporosis and low bone density are common in people in the early stages of multiple sclerosis (MS), according to a new study published in the Neurology®, the medical journal of the American Academy of Neurology.

Saturday, July 16th, 2011

We’ve known that people who have had MS for a long time are at a greater risk of low bone density and broken bones, but we didn’t know whether this was happening soon after the onset of MS and if it was caused by factors such as their lack of exercise due to lack of mobility, or their medications or reduced vitamin D from lack of sun exposure,” said study author Stine Marit Moen, MD, of Oslo University Hospital Ulleval in Norway.

Research has shown Omega-3 fatty acids found in fish oil specifically EPA and DHA ,  are positively associated with bone mineral accrual and, thus, with peak BMD in young men.” Higher bone density in youth can decrease the chances of brittle bones and osteoporosis later in life.

Low vitamin D levels are associated with an increased risk of MS. Low vitamin D levels can lead to reduced calcium absorption and bone mineralization, or the process the body uses to turn minerals into bone structure.
“Our hypothesis was that if vitamin D exerts a major effect on the risk of MS, then the effects of low vitamin D levels on bone density would be apparent soon after the onset of MS,” Moen said.
The study involved 99 people with an average age of 37 who were recently diagnosed with MS or clinically isolated syndrome, which means they had a first episode of symptoms like those in MS but have not yet been diagnosed with the disease. All had no or minor physical disability from the disease.
The participants had bone density tests an average of 1.6 years after the first time they had any symptoms suggestive of MS. Their tests were compared to bone tests of 159 people of similar age, gender and ethnicity who did not have the disease.
A total of 51 percent of those with MS had either osteoporosis or osteopenia, compared to 37 percent of those who did not have the disease. Osteoporosis is a disease where low bone density causes the bones to become thin and brittle, making them more likely to break. Osteopenia is low bone density that is less severe than osteoporosis but puts a person at risk for osteoporosis.
The results remained the same after researchers adjusted for other factors that can affect bone density, such as smoking, alcohol use and hormone treatment.
“These results suggest that people in the early stages of MS and their doctors need to consider steps to prevent osteoporosis and maintain good bone health,” Moen said.

The presence of omega-3 fatty acids in young men is linked to “peak bone mass” or bone mineral density, according to a study published in the American Journal of Clinical Nutrition. The study found that 22-year-old men with the highest levels of omega-3 fatty acids had the greatest bone density in the body and spine two years later.

Dr. Magnus Hogstrom and colleagues from Umea University in Sweden followed 78 healthy young men from their mid-teens to early adulthood. The team measured the BMD (bone mineral density) of the total body, hip and spine at the start of the study and again when the participants were 22 and 24 years of age. The objective was to quantify a relationship between the levels of omega-3 fatty acids and bone density.

According to the journal, “The results showed that Omega-3 fatty acids,  are positively associated with bone mineral accrual and, thus, with peak BMD in young men.” Higher bone density in youth can decrease the chances of brittle bones and osteoporosis later in life.

As well as that the EPA in omega3 is one of the most potent  natural anti inflammatory as detailed in previous blogs , as a result the EPA will reduce any inflammation naturally as there is a clear relationship with osteoporosis and inflammation the EPA will target the site of inflammation and reduce it.

Although osteoporosis is often associated with women, the American Osteoporosis Foundation reports that two million American men have osteoporosis. Inadequate physical exercise, smoking and use of antacids that contain aluminum are among risk factors.

Recent research by NASA has also shown that omega3 is a key factor in preventing bone density loss during space travel and they advise that this has important implications for those at risk or suffering from osteoporosis

Omega 3 Fish Oil

Friday, June 3rd, 2011

TakeOmega3 is currently the highest concentration omega3 available and each capsule contains 750mg EPA which is the most powerful natural anti inflammatory and 50mg DHA . EPA actually produces anti inflammatory hormones

It has multiple applications in a clinical and sports setting -

This formulation lowers risk of death from heart disease, heart attack and stroke by preventing clots , decreasing inflammation in the vessels , decreasing cholesterol and stabalizing the heartbeat to prevent irregular contractions
Reduces inflammation in the body which helps conditions such as Arthritis and Inflammatory Bowel Disease , Type 2 Diabetes , Eczema and Psoriasis – EPA is now recognised as the most powerful natural anti inflammatory
Improves mood and concentration especially under stressful conditions , also speeds recovery from traumatic brain injury and recent studies have been looking at the benefits for combat aircraft pilots re improvement in cockpit skills .
Offers better oxygen delivery to the body as a result less muscle fatigue and removes carbon dioxide / lactic acid .
Research is now focusing on the fact it may help prevent osteoporosis
Research is now showing that omega 3 can be linked with a reduction risk of breast cancer , bowel/colon cancer and prostate cancer by as much as 40%
It helps prevent muscle wastage during illness , specifically with regards Cancer and aging as well being the only effective treatment with regards Cancer Malnutrition .
It improves weight loss especially around stomach area
Lowers triglycerides by 20% to 50%
lowers blood pressure
Helps improve bone mass

In athletes it improves stamina and performance , supports mental concentration and focus . Also assists in quicker recovery time after injury

Omega 3 Fish Oil benefits help prevent muscle loss in breast cancer and protects immune system

Tuesday, April 12th, 2011

Fish oil supplements may help prevent muscle loss in breast cancer survivors and help them ward off other chronic diseases, new research from Australia suggests.The study suggests there are clear benefits fish oil supplementation.

Loss of muscle mass shortly after cancer treatment is a common problem for breast cancer survivors.

The problem may be partly due to the presence of chronic inflammation, which causes a breakdown in muscle tissue.

But fish oils interfere with inflammation, thereby reducing its effect.

University of Queensland researcher Cameron McDonald says exercise is effective in rebuilding lost muscle but it’s often hard to maintain over time.

He says muscle loss exposes survivors to the prospect of earlier onset, or exacerbated, obesity-related chronic diseases such as cardiovascular disease and diabetes.

“If fish oil supplementation is effective in preventing muscle loss before it occurs, or even more effective when used in conjunction with exercise, it could significantly decrease the risk of survivors developing a chronic disease,” the PhD student says.

Research is still in its early stages and clinical trials are set to start later in the year.

Omega 3 stronger than any other anti inflammatory

Wednesday, December 15th, 2010

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects”

Omega-3s may reduce inflammation by acting on a receptor found in fat tissue and on inflammatory immune cells called macrophages, according to research.

The new research published in the journal Cell, suggests the mechanisms behind omega-3’s actions as an anti-inflammatory are due to its action on G-protein-coupled receptor 120 (GPR120) working as an omega-3  FA receptor/sensor.

“Omega-3s are very potent activators of GPR120 on macrophages – more potent than any other anti-inflammatory we’ve ever seen,” said lead researcher Dr Jerrold Olefsky of the University of California, San Diego.

Anti-inflammatory

Omega-3 fatty acids have been long associated with anti-inflammatory effects; however the mechanisms behind such effects have been poorly understood.

GPR120 is a G protein-coupled receptor (GPCRs) – part of a group involved in many important cell functions, and is the target of many drugs.

Previous research has suggested that five GPCRs – including GPR120 included – respond well respond to free fatty acids.

Since chronic tissue inflammation is linked to insulin resistance in obesity, the researchers used GPR120 knock-out mice to investigate if omega-3 leads to GPR120-mediated anti-inflammatory and insulin sensitizing effects in vivo.

Robust effect

Researchers found that GPR120 functions as an omega-3 receptor in pro-inflammatory macrophages and mature adipocytes.

When knock-out mice were fed a high-fat diet and treated with omega-3 fatty acids, they showed all the signs of inflammation and the insulin resistance that leads to diabetes with omega-3 having no effect.

Normal mice on a high-fat diet still gained weight, however, omega-3s “had a really robust effect in preventing inflammation,” Olefsky said.

The study also observed that by signalling through GPR120, omega-3 fatty acids mediate potent anti-inflammatory effects to inhibit certain key inflammatory signaling pathways.

The study reports that omega-3 treatment was as effective – or in some cases more effective – than the popular insulin-sensitizing drug Rosiglitazone.

The researchers noted that activation of GPR120 by omega-3s blocks not one, but all inflammatory pathways.

Interpretation

Olefsky said his team focused on GPR120 from the beginning because of where it is found – in fat tissue and on macrophages. Olefsky noted that if your goal is to fight inflammation then “that’s just where you’d want them to be expressed.”

How these findings can be interpreted for humans is not yet clear, but with a growing trend in omega-3 supplementation and increased dietary intakes of omega-3 a goal for many consumers.

Olefski says it is too early to make any formal reccomendations at the moment, but highlights that he does not see any problem with people taking omega-3 supplementations “as long as it isn’t in enormous doses.”

Olefski said that further research needs to be conducted into several – currently unknown – omega-3 mechanisms. For one, omega-3s seems to block the migration of macrophage cells into tissues – “It’s a remarkable effect, and we don’t know its action,” he added.

Source: Cell

Vol 142(5) pp. 687 – 698, doi: 10.1016/j.cell.2010.07.041

“GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects”


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