Posts Tagged ‘3 fish oil’

The best anti aging supplement for a beautiful glowing skin.

Thursday, July 14th, 2011

Get beautiful skin by taking omega 3 fish oil daily high in EPA it will reduce wrinkles and give you a glowing skin
Inflammation is at the basis of virtually every disease process such as cancer, Alzheimer’s disease, heart disease, and wrinkled skin .Essential fatty acids omega3 fish oil EPA and DHA fish oil nourish the skin, giving it a radiant and beautiful appearance.
to prevent inflammation which leads to skin’s aging and thinning you should eat plenty of fresh fruit and veg , drink water and eat oily fish such as salmon or sardines or take a daily high EPA omega 3 fish oil supplement.
cigarette smoke causes blood vessels to constrict, especially in the skin, resulting in lack of oxygen and nutrients, which accelerates skin aging Omega 3 EPA dilates your blood vessels and ensures better oxygen delivery this ensuring an anti aging effect on the skin working from the inside out .
EPA has also had succeess in the treatment of pro inflammatory conditions such as psoriasis , eczema, acne and spots .
Alcohol not only dehydrates us but causes a pro inflammatory reaction and when we are dehydrated, our skin looks terrible and we are also in a pro-inflammatory – state that accelerates the aging process. You can take steps to address this by taking a daily omega3 supplement high in EPA , eating fresh fruit and veg and also drinking water . It goes without saying that the lower your alcohol intake the better
To counteract inflammation on a cellular level take a daily omega3 fish oil -supplement high in EPA- EPA is the most powerful natural anti inflammatory. Face creams mainly have a cosmetic effect on your skin , to really change your skin you need to change it from the inside and taking omega3 daily helps you do that Omega-3 oils are powerful, natural anti-inflammatory – in fact EPA is the most powerful anti inflammatory so ensure your omega3 has a high level of EPA – omega 3 fish oil also nourish the brain and therefore can alleviate mental depression, EPA again is key in mental health and is as effective as Prozac in the treatment of depression it is used by the prestigious Priory Roehampton London . Omega 3 fish oil also helps nourish the immune system, and therefore help prevent infection and cancer. And essential fatty acids nourish the skin, giving it a radiant and beautiful appearance Try taking one capsule per day of TakeOmega3 with the highest levels of EPA at 750mg per capsule and see the difference in your skin within 30 days .

boosting omega-3 intake through diet or supplements might be a safer way to improve insulin sensitivity in patients with diabetes or pre-diabetes as well as helping to prevent retinopathy a major form of blindness

Wednesday, July 13th, 2011

Omega-3 fatty acids -fats commonly found in fish oil specifically EPA and DHA — were shown several years ago to prevent retinopathy, a major form of blindness, in a mouse model of the disease. A follow-up study, from the same research team at Children’s Hospital Boston, now reveals exactly how omega-3’s provide protection, and provides reassurance that widely used COX-inhibiting drugs like aspirin and NSAIDs don’t negate their benefit.
The findings, published in the February 9th issue of Science Translational Medicine, also suggest that omega-3’s may be beneficial in diabetes.
Retinopathy — an eye disease caused by the proliferation of tortuous, leaky blood vessels in the retina — is a leading cause of blindness, affecting 4.1 million Americans with diabetes (a number expected to double over the next 15 years) and many premature infants. Another 7 million-plus Americans have age-related macular degeneration (AMD); this too will increase as the population ages. The most common “wet” form of AMD is also caused by abnormal blood vessel growth.
The ability to prevent these “neovascular” eye diseases with omega-3 fatty acids could provide tremendous cost savings, says Children’s ophthalmologist Lois Smith, MD, PhD, senior investigator on the study. “The cost of omega-3 supplementation is about $10 a month, versus up to $4,000 a month for anti-VEGF therapy,” she says, referring to drugs such as Macugen and Lucentis used in AMD and diabetic retinopathy. “Our new findings give us new information on how omega-3s work that makes them an even more promising option.”
Omega-3 fatty acids, highly concentrated in the retina, are often lacking in Western diets, which tend to be higher in omega-6 fatty acids. In Smith’s previous study, mice fed diets rich in omega-3 fatty acids by Smith’s team had nearly 50 percent less pathologic vessel growth in the retina than mice fed omega-6-rich diets. Smith and colleagues further showed that the omega-3 diet decreased inflammatory messaging in the eye.
In the new study, they document another protective mechanism: a direct effect on blood vessel growth (angiogenesis) that selectively promotes the growth of healthy blood vessels and inhibits the growth of abnormal vessels.
In addition, Smith and colleagues isolated the specific compound from omega-3 fatty acids that has these beneficial effects in mice (a metabolite of the omega-3 fatty acid DHA, known as 4-HDHA), and the enzyme that produces it (5-lipoxygenase, or 5-LOX). They showed that COX enzymes are not involved in omega-3 breakdown, suggesting that aspirin and NSAIDs — taken by millions of Americans — will not interfere with omega-3 benefits.
“This is important for people with diabetes, who often take aspirin to prevent heart disease, and also for elderly people with AMD who have a propensity for heart disease,” says Smith. (One drug used for asthma, zileuton, does interfere with 5-LOX, however.)
Finally, the study demonstrated that 5-LOX acts by activating the PPAR-gamma receptor, the same receptor targeted by “glitazone” drugs such as Avandia, taken by patients with type 2 diabetes to increase their sensitivity to insulin. Since these drugs also increase the risk for heart disease, boosting omega-3 intake through diet or supplements might be a safer way to improve insulin sensitivity in patients with diabetes or pre-diabetes. “There needs to be a good clinical study in diabetes,” Smith says.
Smith works closely with principal investigators at the National Eye Institute who are conducting an ongoing multicenter trial of omega-3 supplements in patients with AMD, known as AREDS2. The trial will continue until 2013. An earlier retrospective study, AREDS1, found higher self-reported intake of fish to be associated with a lower likelihood of AMD.
In addition, Smith is collaborating with a group in Sweden that is conducting a clinical trial of omega-3 fatty acids in premature infants, who are often deficient in omega-3. That study will measure infants’ blood levels of omega-3 products and follow the infants to see if they develop retinopathy. If results are promising Smith will seek FDA approval to conduct a clinical trial in premature infants at Children’s.
Meanwhile, in her lab work, Smith plans to continue seeking beneficial lipid pathways, while looking for the most harmful omega 6 metabolites. “We found the good guys, now we’ll look for the bad ones,” says Smith. “If we find the pathways, maybe we can selectively block the bad metabolites. We would hope to start with drugs that are already available.”
Przemyslaw Sapieha and Andreas Stahl in Smith’s lab were co-first authors on the study. Funders include the National Eye Institute, the Children’s Hospital Boston Mental Retardation and Developmental Disabilities Research Center, Research to Prevent Blindness, the Alcon Research Institute, MacTel Foundation, the Roche Foundation for Anemia Research and the V. Kann Rasmussen Foundation.

Omega-3 fatty acids EPA and DHA , combined with two blood-thinning drugs, significantly changed the blood-clotting process and may reduce the risk of heart attacks in patients with stents in their heart arteries, according to research reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

Wednesday, July 13th, 2011

Foods rich in omega-3, such as salmon and other oily fish, have been previously shown in other studies to reduce the risk of heart problems in people with coronary artery disease. In this study, the participants were given the pill form of omega-3 (1,000 milligrams n-3 PUFA daily) and were encouraged to increase their consumption of oily fish.
This study sought to determine what effects omega-3 might add to those of aspirin and clopidogrel.
“There are no other studies on omega-3 effects in patients who were already being treated with optimal medical therapy after stent placement,” said Grzegorz Gajos, M.D., Ph.D., lead author and assistant professor of cardiology at Jagiellonian University in Krakow, Poland. “This was a proof of concept study. We were looking for any effect and what it might be.”
The Omega-PCI Study — a double-blind, placebo-controlled trial — found patients who received the omega-3 pills with aspirin and clopidogrel had blood clots more susceptible to destruction than patients who received only the two blood thinners.
The research team particularly targeted the protein fibrin and the interlaced structure it forms in coagulated blood.
Gajos and colleagues examined findings from 54 patients (41 men, 13 women, average age 62.8 years) who participated in the trial conducted at John Paul II Hospital in Krakow.
This study evaluated the effects of omega-3 in patients with stable coronary artery disease who had their clogged heart arteries opened by a catheter procedure and a stent successfully inserted to help keep the vessels opened. Previously, the researchers had reported that adding omega-3 to the clopidogrel antiplatelet drug after stenting significantly lowered the platelet response in clotting.
For this study researchers randomly selected 24 patients as controls and 30 for treatment before their heart procedures. Both groups received the same daily doses of aspirin and clopidogrel for four weeks after stenting. The treatment group received 1,000 milligrams of omega-3 daily and the controls received a placebo each day.
The study showed that, in comparison with the control group, the omega-3 treated patients:
Produced less of a clotting factor called thrombin.
Formed clots with an altered and favorable structure — including larger pores — that made them easier to disrupt. Therefore the clot-destruction time was 14.3 percent shorter. This might prove important in protecting patients, especially those with drug-eluting stents who occasionally develop potentially fatal late clots.
Had less oxidative stress.
Showed no significant changes in fibrinogen and clotting factor (II, XIII) levels. Fibrinogen is a protein produced by the liver. This protein helps stop bleeding by helping the formation of blood clots.
Fibrinogen is converted by thrombin into fibrin during blood coagulation. The implication of this finding suggests that changes in the three biomolecules had no role in reducing the treatment group’s thrombin generation and altering the structure of blood clots that formed, Gajos said.
“Our study suggests that combined moderate anti-thrombotic and anti-platelet actions of omega-3, when added to those of other treatments, may improve outcomes for coronary artery disease patients,” Gajos said.
Study participants experienced only mild adverse side effects and the number of events did not vary significantly between the two groups. There were not enough participants to assess clinical benefit from the changes in the clotting process.
Another limitation of the study was the inability to extrapolate the findings to healthy individuals, those with a high coronary artery disease risk, and those not taking aspirin and/or clopidogrel.

Omega 3 Fish Oil Improves Lung Function in Asthmatics During Exercise

Tuesday, July 12th, 2011

Omega 3 fish Oil specifically EPA from marine sources such as fish ie sardines , anchovies have anti-inflammatory effects in respiratory tissues in people with asthma, . Recently,  omega-3 fish oils were found to ease breathing in elite athletes with exercise-induced airway narrowing. Now, they appear to help asthmatics during exercise, too.

Researchers at the Indiana University School of Medicine, USA, compared the effect of 3 weeks of fish or olive oil supplementation on lung function in asthmatic patients. Participants were tested by treadmill exercise and had their lung function and use of bronchodilators measured before, during, and after exercise. When the patients consumed the fish oil supplements, they reduced their use of bronchodilators by nearly a third and experienced significantly improved lung function compared to their performance when consuming olive oil or a normal diet. The usual decline in lung function with exercise and a normal diet was reduced by 64% during the period of fish oil consumption. These responses were accompanied by corresponding changes in immune responses in white blood cells, and reduced production of pro-inflammatory chemical mediators.

These findings suggest an additional strategy to ease the breathing difficulties associated with exercise, particularly in cold conditions. These results also support current understanding of how omega 3 fish oil specifically EPA  suppress inflammatory responses in asthma and exercise induced asthma  and other clinical conditions with exaggerated immune responses.

Omega3 EPA best for Heart Health and LDL Cholesterol reductions

Monday, July 11th, 2011

Omega 3 EPA reduces LDL cholesterol levels – TakeOmega3 has 750mg EPA per capsule

New clinical study results presented at the American Heart Association Scientific Sessions show that the long-chain omega-3 fatty acid EPA (eicosapentaenoic acid), helped significantly reduce small dense LDL (bad) cholesterol levels.

“This study suggests that supplementation with the omega-3 fatty acid EPA may present unique benefits for cardiovascular health,” said Sujata K. Bhatia, M.D., Ph.D., research associate with DuPont. “EPA was shown to have advantageous effects on several biomarkers, including LDL cholesterol, small dense LDL, and lp-PLA2.”

EPA is a long-chain fatty acid that is found primarily in cold water, fatty fish like sardines anchovies mackerel as well as some omega-3 fatty acid such as TakeOmega3 which has 750 mg EPA per capsule and is the highest grade omega 3 available in UK . A growing body of evidence suggests that EPA is the long-chain omega-3 that supports heart health.

The study, conducted by Cardiovascular Research Associates and sponsored by DuPont, was conducted among 110 healthy individuals comparing the effects of EPA supplements to DHA (docosahexaenoic acid) supplements on cardiovascular health. The participants were placed into four study groups and examined over a six week period. During that time, each group was monitored while taking: EPA 600 mg per day; EPA 1,800 mg per day; DHA 600 mg per day; and an olive oil placebo.

The study found that in the 1,800mg EPA group, there were significant reductions of 7 percent for small dense low density lipoprotein (LDL) cholesterol, and 6 percent for lipoprotein-associated phospholipase A2 (lp-PLA2). lp-PLA2 is an enzyme involved in vascular inflammation.
In contrast, the 600mg DHA group showed a significant increase in total small dense LDL cholesterol in both the fasting and fed state of 14.2 percent and 16.3 percent respectively.

The study results will be featured during the American Heart Association Conference poster session in Chicago

Lower Breast Cancer Events in Survivors with Higher Omega-3 fish oil Consumption- specifically EPA

Sunday, July 10th, 2011

Links between the chance of developing breast cancer and the consumption of fat or individual fatty acids have been around for years, but the research findings have been all over the map. Animal and cell culture studies have often reported links between omega-3 fatty acids from seafood and lower growth and spread of breast cancer tumors, but these findings have not consistently carried over into human studies. Nevertheless, the topic continues to be investigated. A systematic review of the scientific literature a few years ago analyzed 10 studies in humans and concluded there was about a 30% lower risk of breast cancer in women with higher intakes of seafood omega-3s.

Investigators in California asked a different question about the possible links between fish or omega-3 consumption and breast cancer. They focused on breast cancer survivors. The researchers asked whether omega-3 intakes affect a woman’s disease-free survival or subsequent breast cancer events after she has been treated for early-stage breast cancer. Participants in the study were enrolled in the Women’s Healthy Eating and Living Study, which was designed to learn whether eating more vegetables, fruits and fiber affected the risk of recurrent or new primary breast cancer. The study included women from the ages of 18 to 70 who were monitored over a 7-year period.

Food intake information was obtained when the women entered the study. The women were assessed for their health outcomes and the development of any cancer at intervals from 1 to 6 years after the study began. At the beginning of the study, the women consumed an average of 186 mg per day of the long-chain omega-3s found in seafood. This is nearly double the amount consumed by the general population.

After 6 years, their intake had increased to 237 mg per day, an increase of 27%. This change was unrelated to the study. Women’s use of fish oil supplements also increased during that time from 4% to 10% of women. The investigators found that the increase in omega-3s was significant for women who did not experience additional breast cancer events, but not among those who had additional events. An “event” was considered to be a recurrent cancer or a new invasive breast cancer.
The key finding was that women in the upper two-thirds of long-chain omega-3 intakes experienced a 25% reduction in the likelihood of developing an additional breast cancer event. Higher omega-3 intakes ranged from a median of 73 to 365 mg per day. It made no difference whether the omega-3s came only from food or from food plus supplements. The investigators also noted that women in the highest third of omega-3 consumption were 40% less likely to die from breast cancer compared with women in the lowest third of omega-3 consumption. The cutoff for the highest omega-3 intake was 153 mg/day or more.

Omega 3 fish oil Supplementation specifically EPA Linked to Improved Behaviors in ADHD Subgroups

Sunday, July 10th, 2011

Attention deficit hyperactivity disorder (ADHD) is a heterogeneous, clinically recognized condition characterized by impulsivity, inattention and hyperactivity. Children with ADHD often have symptoms overlapping other disorders, such as coordination problems, dyslexia, social difficulties and cognitive deficits. ADHD occurs most commonly in children, but in a majority of cases some symptoms persist into adolescence and adulthood.

Long-chain omega-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and other PUFAs have been associated with the condition because of their importance in brain structure and function, processing of emotional responses, low concentrations in ADHD and limited success in treating individuals with the condition. However, not all studies have reported low PUFA status in ADHD or treatment effectiveness with n-3 LC-PUFAs. Several intervention studies have used a combination of n-3 and n-6 fatty acids. Studies using a relatively high proportion of eicosapentaenoic acid (EPA) have reported improvement in some symptoms, depending on the type of ADHD the children exhibited. Pure DHA was without effect in one study. ADHD behaviors may be predominantly combined hyperactive/impulsive, oppositional/defiant or inattentive and it is not known which type(s) of ADHD might be most responsive to treatment with EPA, n-3 LC-PUFAs or combined n-3 and n-6 fatty acids.

A recent double-blind, controlled study from Sweden explored whether children with clinically diagnosed combined type ADHD or subgroups of these children would respond to EPA supplementation. The investigators recruited children aged 7 to 12 years from 8 psychiatric and pediatric clinics in the country. Participants were free of other medical conditions, mental retardation, autism and epileptic seizures during the preceding 2 years. Various other clinical conditions, such as endocrine disorders, impaired hearing or vision and psychotic symptoms were also reasons for exclusion. Of the 109 eligible children, 17 dropped out, leaving 92 for intention-to-treat analysis. Additionally, 10 more had deficient follow-up data, leaving 82 participants with complete data.

After 15 weeks In the teachers’ subscale for inattention or cognitive difficulties, children who consumed the EPA supplement exhibited significant improvement. When the investigators analyzed the results for the children who were classified at baseline as having oppositional behaviors, the effect of EPA treatment on the combined scores of parents’ and teachers’ ratings was statistically significant (P = 0.03). This result was largely attributable to scores on the teachers’ ratings. Among these children, 52% of those who consumed the EPA supplement exhibited a 25% improvement or more, according to the teachers’ ratings for oppositional behavior and inattention or cognitive problems. Those who responded to the EPA supplement also had lower serum phospholipid EPA and higher arachidonic acid concentrations at baseline compared with non-responders (Table).

Qb-test scores for hyperactivity in children who were below the median at baseline improved by 25% or more in 36% of children who consumed the EPA supplement compared with 18% in the placebo group. However, these improvements did not reach statistical significance. In 22 children who were both hyperactive and oppositional-defiant, 13 consumed EPA and 9 received the placebo. Eight of the EPA children showed a 25% or greater improvement in hyperactive and oppositional behavior, while only one in the placebo group improved. These responses were significant, P = 0.03.

In this study, subgroups of children with ADHD who had either oppositional or hyperactive-impulsive behaviors responded to the consumption of EPA with significant reductions in their symptoms as assessed by their teachers. These findings support those of Richardson and colleagues and Johnson’s research group research group who used a combination of fatty acids in particular subgroups of children with ADHD. Those with inattention or oppositional behavior are more likely to respond to EPA or n-3 LC-PUFAs, while those with hyperactivity may be less responsive. The study also observed that teachers’ ratings are more likely to detect behavioral changes than those from parents. Many problem behaviors occur in the classroom, so this observation was not surprising. In this study, children with oppositional behaviors who responded to EPA had significantly lower levels of EPA in their serum phospholipids compared with non-responders, although the number of children was very small. The authors also noted that the dose of EPA, 500 mg/day, was relatively small, but sufficient to be useful in subgroups of the participants.

Omega 3 EPA  fish oil supplementation improves teacher-rated behaviour and oppositional symptoms in children with ADHD

Omega 3 EPA success potential in the treatment and prevention of bowel cancer

Saturday, July 9th, 2011

Omega 3 fish oil EPA success potential in the treatment and prevention of bowel cancer

RESEARCHERS from  Leeds University Yorkshire are planning to carry out a series of experiments to investigate if omega 3 fish oil specifically EPA can prevent or treat the spread of bowel cancer to the liver.

Scientists from Leeds University will test a naturally occurring omega-3 fish oil component.

Gastroenterologist Prof Mark Hull, from the Leeds Institute of Molecular Medicine, will design a clinical trial to test the effect in humans at risk of or with bowel cancer which has spread to the liver.

The research is being funded by the charity Yorkshire Cancer Research and follows a previous trial in Leeds that showed that fish oil, or pure Eicosapentaenoic Acid (EPA), may prevent bowel polyps, the precursors of cancer.

Prof Hull said: “We and others have already demonstrated that EPA omega3 may  have beneficial effects at a later stage after development of malignancy.

TakeOmega3 has 750mg EPA AND 50mg DHA per capsule it is an 85% concentrate most other omega3’s are around 40%  and contain other oils within the capsule the key to successful treatment of this and other medical conditions  is to use as high a concentration of EPA as possible  , uniquely it is the highest concentration EPA supplement available and is manufactured in MHRA facilities thus adheering to the highest possible standards normally only applied to pharmaceutical drugs.

Bowel Cancer or Colorectal around 110 new cases of colorectal cancer are diagnosed each day in the UK and it is the third most common cancer after breast and lung. In 2008 there were 39,991 new cases of large bowel cancer registered in the UK: around two-thirds (25,551) in the colon and one-third (14,440) in the rectum

Scotland has one of the highest rates of bowel cancer worldwide, which has been linked to a range of social and economic factors such as significant deprivation, poor diet choices, high alcohol consumption, lack of exercise and an ageing population.
Around 3,500 people are diagnosed with bowel cancer each year in Scotland and over 1,500 die of the disease.
Bowel cancer is the third most common cancer in the Western world and is the second biggest cause of cancer-related death after lung cancer. However, the disease is highly treatable if detected early, with a 90% survival rate over five years.

Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain.

Saturday, July 9th, 2011

Abstract
BACKGROUND:
The use of NSAID medications is a well-established effective therapy for both acute and chronic nonspecific neck and back pain. Extreme complications, including gastric ulcers, bleeding, myocardial infarction, and even deaths, are associated with their use. An alternative treatment with fewer side effects that also reduces the inflammatory response and thereby reduces pain is believed to be omega-3 EFAs found in fish oil specifically EPA. We report our experience in a neurosurgical practice using fish oil supplements for pain relief.

METHODS:
From March to June , 250 patients who had been seen by a neurosurgeon and were found to have nonsurgical neck or back pain were asked to take a total of 1200 mg per day of omega-3 EFAs (eicosapentaenoic acid and DHA )found in fish oil supplements. A questionnaire was sent approximately 1 month after starting the supplement.

RESULTS:
Of the 250 patients, 125 returned the questionnaire at an average of 75 days on fish oil. Seventy-eight percent were taking 1200 mg and 22% were taking 2400 mg of EFAs. Fifty-nine percent discontinued to take their prescription NSAID medications for pain. Sixty percent stated that their overall pain was improved, and 60% stated that their joint pain had improved. Eighty percent stated they were satisfied with their improvement, and 88% stated they would continue to take the fish oil. There were no significant side effects reported.

CONCLUSIONS:
Our results mirror other controlled studies that compared ibuprofen and omega-3 EFAs demonstrating equivalent effect in reducing arthritic pain. omega-3 EFA fish oil supplements appear to be a safer alternative to NSAIDs for treatment of nonsurgical neck or back pain in this selective group.
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Side Effects Fish Oil

Friday, April 15th, 2011

People are often concerned about the side effects of fish oil . As with any supplement there is always the chance of suffering side effects however the best way to avoid side effects with fish oil is very simple.

Buy a good quality fish oil supplement that is highly purified , this should mean that you avoid the fishy aftertaste and gastric / stomach upset that can be linked with lower grade fish oil . Unfortunately it isnt always clear how pure a product is, but a good guideline is to look at the omega3 content per fish oil supplement and then see what the level of the active ingredients EPA and DHA are in percentage to the total omega 3 fish oil. For example a product may detail it is 1000mg omega 3 fish oil however the level of  active ingredients EPA and DHA may only be 300mg – so less than a 1/3 of the  total oil contains the important EPA /DHA  so this is clearly a low concentration oil which has not been refined to the extent of a high quality oil such as takeomega 3 fish oil . A good quality fish oil supplement will detail the exact levels of EPA and DHA per capsule . Take Omega 3 fish oil has per fish oil supplement 750mg EPA and 50mg DHA and is the highest concentration available of any fish oil supplement at 85% concentration.

Do you know where the fish oil has been sourced from ?  What is the testing process throughout manufacturing process ? Where is the country of origin ? All of these should be considered as it is an indication of the purity of the fish oil , and the purity of the fish oil could be critical in avoiding stomach upset , nausea, gastric upset. Take Omega 3 fish oil is uniquely made from fish sourced from sustainable fish stocks from the purest waters of Chile – only sardines and anchovies are used in our fish oil. The refining process takes 10 weeks and is uniquely carried out in only one of two sites globally licensed by MHRA (Medical Health and Regulatory Authority) as a result Take Omega 3 is the highest concentration available . So the fish oil side effects that you may experience with other less refined fish oils due to lack of  purity and low concentration dont occur.

As with any supplement fish oil isnt any different and you should stick to the recommended dosage – we recommend 1 fish oil supplement per day  as that delivers 750mg EPA and 50mg DHA- obviously other  fish oil supplement brands have far lower concentrations and therefore they may recommend you  take multiple capsules. The more low grade omega 3 fish oil  capsules you take the more chance you are likely to have side effects fish oil .

If  you take blood thinners such as warfarin you should consult your Doctor  as omega 3 does have a blood thinning effect . Unlike St Johns Wort omega 3 fish oil does not interact in a negative way with any other prescription medicine so it is safe though you should always advise your GP that you are taking it as with any other vitamin / mineral supplement.

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