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Two double-blind placebo-controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia. Peet M1, Brind J, Ramchand CN, Shah S, Vankar GK.
Academic Department of Psychiatry, Northern General Hospital, The Longley Centre, Norwood Grange Drive, S5 7JT, Sheffield, UK. m.peet@sheffield.ac.uk
Abstract
Evidence that the metabolism of phospholipids and polyunsaturated fatty acids (PUFA) is abnormal in schizophrenia provided [...]
Two double-blind placebo-controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia. Peet M1, Brind J, Ramchand CN, Shah S, Vankar GK.
September 9th, 2015Omega 3 and cancer the facts
March 15th, 2014Tweet
Omega-3 supplements linked to prostate cancer” (Fox News) “Omega-3 supplements could raise prostate risk” (Telegraph)
“Fish oil supplements linked to prostate cancer” (Health News) “Men who take omega-3 supplements at 71 percent higher risk of prostate cancer” (NY Daily News) “Omega-3 supplements may trigger prostate cancer” (Nursing Times) “Hold the salmon: Omega-3 fatty acids linked to [...]
prostate cancer and Omega3 EPA
November 16th, 2013Tweet
EPA, COQ10 Reduced Serum PSA Levels
Safarinejad MR, Shafiei N, Safarinejad S. Effects of EPA, γ-linolenic acid or coenzyme Q10 on serum prostate-specific antigen levels: a randomised, double-blind trial. Br J Nutr. 2012 Nov 30:1-8.
The main objective of the present study was to determine the potential of n-3 and n-6 fatty acids or coenzyme Q10 [...]
Omega-3 PUFA Inhibit Human Breast Cancer Cell Growth
November 16th, 2013Tweet
Omega-3 PUFA Inhibit Human Breast Cancer Cell Growth
Cao W, Ma Z, Rasenick MM, et al. N-3 poly-unsaturated Fatty acids shift estrogen signaling to inhibit human breast cancer cell growth. PLoS One. 2012;7(12):e52838.
Although evidence has shown the regulating effect of n-3 poly-unsaturated fatty acid (n-3 PUFA) on cell signaling transduction, it remains unknown whether n-3 PUFA [...]
Omega-3 Directly Inhibit Breast Cancer Growth
November 16th, 2013Tweet
Omega-3 Directly Inhibit Breast Cancer Growth
MacLennan MB, Clarke SE, Perez K, et al. Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids. J Nutr Biochem. 2013 Jan;24(1):388-95.
INTRODUCTION:
Despite the advocacy that diet may be a significant contributor to cancer prevention, there is a lack of direct evidence from epidemiological and experimental studies to [...]
Carcinogenesis – Chemopreventative Potential Of Omega3 EPA
November 16th, 2013Tweet
Carcinogenesis – Chemopreventative Potential Of EPA
Nikolakopoulou Z, Nteliopoulos G, Michael-Titus AT, et al. Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2. Carcinogenesis. 2013 Jul 26.
The long chain omega-3 polyunsaturated fatty acids (n-3 PUFAs), eicosapentaenoic acid (EPA) and its metabolite docosahexaenoic acid (DHA), inhibit cancer formation in vivo but [...]
Omega-3 FAs Decrease Plasma VLDL-TG Concentration
November 16th, 2013Tweet
Omega-3 FAs Decrease Plasma VLDL-TG Concentration
Wong AT, Chan DC, Ooi EM, et al. Omega-3 fatty acid ethyl ester supplementation decreases very-low density lipoprotein triacylglycerol secretion in obese men. Clin Sci (Lond). 2013 Jan 28.
Dysregulated very-low density lipoprotein (VLDL)-triacylglycerol (TG) metabolism in obesity may account for hypertriacylglycerolaemia and increased cardiovascular disease.
Omega-3 fatty acid ethyl esters (ω-3 [...]
High Concentration Omega3 EPA improves vascular function
November 16th, 2013Tweet
Highly Purified EPA Improves Vascular Function
Sasaki J, Miwa T, Odawara M. Administration of highly purified eicosapentaenoic acid to statin-treated diabetic patients further improves vascular function. Endocr J. 2012;59(4):297-304.
We prospectively examined the additional effects of highly purified eicosapentaenoic acid (EPA) particularly on the vascular function of diabetic patients with hypercholesterolemia receiving statin therapy.
We enrolled [...]
Reduction in brain abnormalities in older adults associated with higher consumption of omega3 fatty acids from oily fish
November 16th, 2013Tweet
Virtanen JK, Siscovick DS, Lemaitre RN, et al. Circulating Omega-3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study. J Am Heart Assoc. 2013 Oct 10;2(5):e000305.
BACKGROUND:
Consumption of tuna or other broiled or baked fish, but not fried fish, is associated with fewer subclinical brain abnormalities on magnetic resonance [...]
High Dose EPA / DHA up to 5g / day DO NOT increase risk of bleeding -European Food Safety Authority
January 16th, 2013Tweet
European Food Safety Authority state
Long-term supplemental intakes of EPA and DHA combined up to about 5 g/day do not increase the risk of spontaneous bleeding episodes or bleeding complications even in subjects at high risk of bleeding (e.g. taking acetylsalicylic acid or anti-coagulants).or affect glucose homeostasis immune function or lipid peroxidation,
DHA at doses of [...]
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